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Whatever the dose (curative or prophylactic), this medicinal product must not be used in the following situations: Hypersensitivity to enoxaparin sodium, heparin or its derivatives, including the other LMWHs; Bleeding or tendency to bleed related to impaired hemostasis (a possible exception to this contraindication may be disseminated intravascular coagulation, when not related to heparin treatment (see Precautions for use under Precautions); Organic lesion likely to bleed; Clinically significant active major bleeding and conditions with a high risk of uncontrolled hemorrhage, including recent hemorrhagic stroke; History of immune mediated heparin-induced thrombocytopenia (HIT) within the past 100 days or in the presence of circulating antibodies (see Precautions).
This medicinal product must not be used at curative doses in the following situations: Intracerebral hemorrhage; Spinal or epidural anesthesia must never be performed in patients under curative LMWH treatment.
